Monckeberg Medial Sclerosis involves calcification of the tunica media in which vessels?

Monckeberg Medial Sclerosis involves calcification of the tunica media in which vessels?

• A. Large Elastic Arteries
• B. Capillaries
• C. Medium Muscular Arteries
• D. Small Arteries

Answer: (C)

Monckeberg medial calcific sclerosis is characterized by calcification of the tunica media in muscular arteries. This pattern occurs in medium-sized muscular arteries (such as the radial or tibial arteries), where the medial deposits stiffen the vessel wall while the lumen is often preserved. Large elastic arteries (like the aorta) have different elastic-layer–rich changes, capillaries lack a muscular layer, and small arteries don’t fit the classic description. So the vessels involved are medium-sized muscular arteries, giving the characteristic “medial” calcification with preserved luminal patency.

Monckeberg medial calcific sclerosis is characterized by calcification of the tunica media in muscular arteries. This pattern occurs in medium-sized muscular arteries (such as the radial or tibial arteries), where the medial deposits stiffen the vessel wall while the lumen is often preserved. Large elastic arteries (like the aorta) have different elastic-layer–rich changes, capillaries lack a muscular layer, and small arteries don’t fit the classic description. So the vessels involved are medium-sized muscular arteries, giving the characteristic “medial” calcification with preserved luminal patency.