Myeloid neoplasia involving hematopoietic precursor cells is ______ polycythemia

Myeloid neoplasia involving hematopoietic precursor cells is ______ polycythemia

• A. Primary
• B. Secondary
• C. Polycythemia Vera
• D. Relative

Answer: (A)

Primary polycythemia refers to an intrinsic, clonal proliferation of hematopoietic precursor cells in the bone marrow that increases red cell mass. This makes it a myeloproliferative neoplasm, arising from the precursor cells themselves rather than from an external stimulus. That distinguishes it from secondary polycythemia, which is driven by elevated erythropoietin in response to hypoxia or ectopic sources, and from relative polycythemia, which results from plasma volume loss rather than a true expansion of red cells. So, when myeloid neoplasia involves hematopoietic precursors, the condition is best described as primary polycythemia (polycythemia vera).

Primary polycythemia refers to an intrinsic, clonal proliferation of hematopoietic precursor cells in the bone marrow that increases red cell mass. This makes it a myeloproliferative neoplasm, arising from the precursor cells themselves rather than from an external stimulus. That distinguishes it from secondary polycythemia, which is driven by elevated erythropoietin in response to hypoxia or ectopic sources, and from relative polycythemia, which results from plasma volume loss rather than a true expansion of red cells. So, when myeloid neoplasia involves hematopoietic precursors, the condition is best described as primary polycythemia (polycythemia vera).